I was going to wait for a stable version 2 but the new models coming out for hexen made me give v2 a try.
I've tried several different builds of V2 and get the same problem with them all.
I'm on Windows 10 but running Classic shell, when I start Doomsday 2 the DE logo comes up and then immediately I get a windows error that Doomsday.exe has quit working and will shut down, no other info given. I can't find a doomsday out for V2 anywhere. I'm using windows 10 pro 64 but have tried both 64bit and x86 builds with same result.
AMD FX8350 8 core
Windows pro 64 (classic shell)
16 gig memory
Vapor-X 5770 video card. 1GB mem